A new study suggests that a pill used for emergency contraception could be repurposed at a higher dose as an abortion drug, providing a possible alternative to mifepristone, one of the two drugs used in the most common type of abortion in the United States.

Major uncertainties remain about the impact of puberty blockers and gender-affirming hormone therapy on children and young people with gender-related distress (gender dysphoria), making it impossible to determine conclusively whether they help or harm, finds two pooled data analyses of the available evidence, published online in the Archives of Disease in Childhood.

The prevalence of psychological distress caused by a mismatch between birth sex and gender identity, formally known as gender dysphoria, likely rose 50-fold nationwide between 2011 and 2021, suggests an analysis of primary care data in England and published online in Archives of Disease in Childhood.